# Do the MRI images match spatially with the resected tumor which cut into tissue blocks in Ivy GAP glioblastoma database?

**URL:** https://community.brain-map.org/t/do-the-mri-images-match-spatially-with-the-resected-tumor-which-cut-into-tissue-blocks-in-ivy-gap-glioblastoma-database/954
**Category:** Science
**Tags:** atlas-human-brain-adult
**Created:** [February 22, 2021, 6:22am UTC](https://community.brain-map.org/t/do-the-mri-images-match-spatially-with-the-resected-tumor-which-cut-into-tissue-blocks-in-ivy-gap-glioblastoma-database/954 "2021-02-22T06:22:14Z")
**Posts on this page:** 1
**Showing post:** 5

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### Author: ![Ralph](https://avatars.discourse-cdn.com/v4/letter/r/f475e1/32.png) [@Ralph](https://community.brain-map.org/u/Ralph)
#### Post date: [February 18, 2022, 2:30am UTC](https://community.brain-map.org/t/do-the-mri-images-match-spatially-with-the-resected-tumor-which-cut-into-tissue-blocks-in-ivy-gap-glioblastoma-database/954/5 "2022-02-18T02:30:19Z")

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Dear AustinKunch,  
Please see my reply to you under your other inquiry: [MRI coordinates of IVY GAP RNAseq data](https://community.brain-map.org/t/mri-coordinates-of-ivy-gap-rnaseq-data/1440):

The Ivy GAP does not have any data based on region, ISH, tissue block, or LMD-RNA-Seq sample that is tied to MRI coordinates. In other Allen Institute atlases, -1 is typically used to represent coordinates with no data (e.g., locations with no anatomical coordinates). There are other users of the Ivy GAP who have attempted to map the histology data, or at least tissue block, to the MRIs, but I am not sure what the status is of these efforts. As I explained to Qin in this forum’s same topic, accurate mapping probably cannot be achieved without multiple stereotactic biopsy MRIs for each patient, which was not done for the Ivy GAP.  
Thank you,  
Ralph

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