# Downloading Gene Grid Data Expression at a higher resolution

**URL:** <https://community.brain-map.org/t/downloading-gene-grid-data-expression-at-a-higher-resolution/538>\
**Category:** Technical\
**Tags:** api, atlas-reference-maps, allensdk\
**Created:** [May 7, 2020, 2:12pm UTC](https://community.brain-map.org/t/downloading-gene-grid-data-expression-at-a-higher-resolution/538 "2020-05-07T14:12:52Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![anorak](https://avatars.discourse-cdn.com/v4/letter/a/e9bcb4/32.png) [@anorak](https://community.brain-map.org/u/anorak)\
**Post date:** [May 7, 2020, 2:12pm UTC](https://community.brain-map.org/t/downloading-gene-grid-data-expression-at-a-higher-resolution/538/1 "2020-05-07T14:12:52Z")

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There is an option to download the gene grid expression data at 200 um resolution. Is it possible to download the grid expression data at a higher resolution say 25 um

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**Author:** ![anorak](https://avatars.discourse-cdn.com/v4/letter/a/e9bcb4/32.png) [@anorak](https://community.brain-map.org/u/anorak)\
**Post date:** [May 7, 2020, 2:30pm UTC](https://community.brain-map.org/t/downloading-gene-grid-data-expression-at-a-higher-resolution/538/2 "2020-05-07T14:30:33Z")

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if not is it possible to download the ish image series for each gene and register it to a reference atlas at 25um resolution to create a higher density map

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**Author:** ![tylermo](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/tylermo/32/155_2.png) [@tylermo](https://community.brain-map.org/u/tylermo)\
**Post date:** [August 24, 2020, 2:58pm UTC](https://community.brain-map.org/t/downloading-gene-grid-data-expression-at-a-higher-resolution/538/3 "2020-08-24T14:58:45Z")

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Hi Anurag,

We only have the 200 um resolution available.

In terms of creating a higher density map at 25 um, it’s technically possible but there are several steps. Two of note:

1. The data were sampled at a 200 um resolution, so you’ll need an interpolation method to fill in the 25 um resolution.
2. You’ll want to start by downloading our ISH and expression data from [AllenSDK](https://allensdk.readthedocs.io/en/latest/allensdk.api.queries.mouse_atlas_api.html). You’ll need to write some software to assign the data into a grid. We have a [software module that does this for connectivity data](https://github.com/AllenInstitute/AllenSDK/tree/master/allensdk/mouse_connectivity); it’s not directly applicable to this case, but conceptually similar.