# MEC Single Nucleus RNA Seq Data

**URL:** <https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280>\
**Category:** General\
**Created:** [March 24, 2025, 3:43pm UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280 "2025-03-24T15:43:03Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![karte](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/karte/32/2185_2.png) [@karte](https://community.brain-map.org/u/karte)\
**Post date:** [March 24, 2025, 3:43pm UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280/1 "2025-03-24T15:43:03Z")

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I am able to located the MTG, DLPFC, and A9 h5ad files in the AWS bucket for single nucleus rna seq data but I can’t locate where the MEC region’s h5ad file is. Does anyone know where this file is located?

Thank you!

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**Author:** ![Susan.Sunkin](https://avatars.discourse-cdn.com/v4/letter/s/6a8cbe/32.png) [@Susan.Sunkin](https://community.brain-map.org/u/Susan.Sunkin)\
**Post date:** [March 28, 2025, 5:11am UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280/2 "2025-03-28T05:11:02Z")

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Hi,

Thank you for your question. Can you provide more context as to which project’s data are you trying to locate the MEC region h5ad file?

Thank you,

Susan

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**Author:** ![karte](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/karte/32/2185_2.png) [@karte](https://community.brain-map.org/u/karte)\
**Post date:** [March 28, 2025, 11:25am UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280/3 "2025-03-28T11:25:08Z")

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Thank you so much for your reply. It is the SEA-AD study’s 10x processed snRNASeq data. The bucket that I see the other brain region files in is this one: [https://sea-ad-single-cell-profiling.s3.amazonaws.com/index.html](https://sea-ad-single-cell-profiling.s3.amazonaws.com/index.html)

Thank you!

Best,  
Kareem

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**Author:** ![jeremyinseattle](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/jeremyinseattle/32/50_2.png) [@jeremyinseattle](https://community.brain-map.org/u/jeremyinseattle)\
**Post date:** [March 28, 2025, 3:35pm UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280/4 "2025-03-28T15:35:08Z")

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Hi @karte,

Currently, the only brain regions with **processed** snRNAseq data are MTG and DLPFC (A9). In addition, we have **raw** data for HIP, MEC, LEC, STG, and V1C available via controlled access at [Sage Bionetworks AD Knowledge Portal](http://adknowledgeportal.synapse.org/Explore/Studies/DetailsPage?Study=syn26223298). Analysis of these data sets is ongoing; when complete, we will post processed data on AWS at the above link.

Best,  
Jeremy

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**Author:** ![karte](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/karte/32/2185_2.png) [@karte](https://community.brain-map.org/u/karte)\
**Post date:** [April 2, 2025, 7:27pm UTC](https://community.brain-map.org/t/mec-single-nucleus-rna-seq-data/4280/5 "2025-04-02T19:27:02Z")

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Got it, thank you!