# SEA-AD BC Matrices Question

**URL:** <https://community.brain-map.org/t/sea-ad-bc-matrices-question/4696>\
**Category:** Science\
**Tags:** sea-ad\
**Created:** [September 12, 2025, 8:27pm UTC](https://community.brain-map.org/t/sea-ad-bc-matrices-question/4696 "2025-09-12T20:27:16Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![eitan.kaplan](https://avatars.discourse-cdn.com/v4/letter/e/5f8ce5/32.png) [@eitan.kaplan](https://community.brain-map.org/u/eitan.kaplan)\
**Post date:** [September 12, 2025, 8:27pm UTC](https://community.brain-map.org/t/sea-ad-bc-matrices-question/4696/1 "2025-09-12T20:27:16Z")

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I am the Scientific Project Manager for the SEA-AD Consortium. I am posting a community question and answer received via email related to working with SEA-AD data:

Q: “I want to work with your MTG snRNAseq data that is available in your AWS open registry. I was wondering if you all used filtered bc matrices or raw bc matrices for the Gabitto et al. paper”

A: We start from the cellranger filtered matrices. Though we have looked at the unfiltered matrices to check if we were missing anything specific (in the severely affected donor exploration).