# Subsetting Mouse Whole Cortex and Hippocampus 10x data by brain region?

**URL:** <https://community.brain-map.org/t/subsetting-mouse-whole-cortex-and-hippocampus-10x-data-by-brain-region/2439>\
**Category:** Transcriptomics Explorer\
**Tags:** atlas-mouse-brain-adult\
**Created:** [July 7, 2023, 5:42pm UTC](https://community.brain-map.org/t/subsetting-mouse-whole-cortex-and-hippocampus-10x-data-by-brain-region/2439 "2023-07-07T17:42:10Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![tylermo](https://yyz1.discourse-cdn.com/flex027/user_avatar/community.brain-map.org/tylermo/32/155_2.png) [@tylermo](https://community.brain-map.org/u/tylermo)\
**Post date:** [July 7, 2023, 7:50pm UTC](https://community.brain-map.org/t/subsetting-mouse-whole-cortex-and-hippocampus-10x-data-by-brain-region/2439/2 "2023-07-07T19:50:44Z")

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Hi Katherine,

We recognize the challenges in unpacking the large 10x matrices. Sufficient memory should help, but the script outlined here may also be of help: [Gene expression matrix.cvs is too large to load it - #17 by jeremyinseattle](https://community.brain-map.org/t/gene-expression-matrix-cvs-is-too-large-to-load-it/566/17)

If you still have issues, feel free to share more specifics here and we can work it through with you.

In general: how big of a file/matrix is _too_ big for you? (Conversely, what size is preferable?)

Tyler

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