# \#alzheimers

**URL:** https://community.brain-map.org/tag/alzheimers/89.md

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## [SEA-AD Multiome problems](https://community.brain-map.org/t/sea-ad-multiome-problems/4550)

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**Author:** [@Victhagas](https://community.brain-map.org/u/Victhagas)\
**Replies:** 3\
**Last updated:** [July 24, 2025, 5:14pm UTC](https://community.brain-map.org/t/sea-ad-multiome-problems/4550 "2025-07-24T17:14:46Z")

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Hi Guys! I was checking the Seattle Alzheimer’s Disease Brain Cell Atlas GitHub page and down at the data location part, I found this: “Briefly, the processed single nucleus RNAseq, ATACseq, and Multiome as well as MERF…

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## [(SEA-AD) For the same donor, is it possible to map the small DAPI section to its IHC counterpart?](https://community.brain-map.org/t/sea-ad-for-the-same-donor-is-it-possible-to-map-the-small-dapi-section-to-its-ihc-counterpart/4108)

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**Author:** [@musikisomorphie](https://community.brain-map.org/u/musikisomorphie)\
**Replies:** 2\
**Last updated:** [February 1, 2025, 10:19am UTC](https://community.brain-map.org/t/sea-ad-for-the-same-donor-is-it-possible-to-map-the-small-dapi-section-to-its-ihc-counterpart/4108 "2025-02-01T10:19:21Z")

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Hi there, I am Jiqing, a post-doc researcher at the Department of Biomedical Engineering, University of Basel. Currently, we are working on a GenAI project that requires exactly paired spatial transcriptomic (ST) and bi…

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## [V1C data from Seattle Alzheimer's Disease Cell Atlas](https://community.brain-map.org/t/v1c-data-from-seattle-alzheimers-disease-cell-atlas/3801)

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**Author:** [@MPanday](https://community.brain-map.org/u/MPanday)\
**Replies:** 2\
**Last updated:** [October 23, 2024, 3:56pm UTC](https://community.brain-map.org/t/v1c-data-from-seattle-alzheimers-disease-cell-atlas/3801 "2024-10-23T15:56:21Z")

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Hello, I’m trying to access V1C (primary visual cortex) data from the Seattle Alzheimer’s Disease Database. According to the documentation, V1C data should be available. However, when I check the AWS bucket for single-c…

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## [Non-anonymized BAM files](https://community.brain-map.org/t/non-anonymized-bam-files/494)

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**Author:** [@rgescudero](https://community.brain-map.org/u/rgescudero)\
**Replies:** 1\
**Last updated:** [March 26, 2020, 6:53pm UTC](https://community.brain-map.org/t/non-anonymized-bam-files/494 "2020-03-26T18:53:10Z")

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I’m interested in analyzing some aberrant splicing events taking place in Alzheimer’s disease, in collaborating with Dr. Jesus Avila. I would like to get acces to the RNA-seq raw data (either fastq or bam files) containi…

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## [Quality check on RNA-seq data from aging.brain-map.org](https://community.brain-map.org/t/quality-check-on-rna-seq-data-from-aging-brain-map-org/420)

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**Author:** [@Chris](https://community.brain-map.org/u/Chris)\
**Replies:** 1\
**Last updated:** [January 29, 2020, 10:10pm UTC](https://community.brain-map.org/t/quality-check-on-rna-seq-data-from-aging-brain-map-org/420 "2020-01-29T22:10:07Z")

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I am comparing the normalised and unnormalised fpkm values between people with Alzheimer’s/Dementia diagnosis and those with no Dementia. However, the difference in fpkm expression of APOE was not found to be significant…
