Brain region dissection procedures

I hope that you are staying well. I am exploring the Developmental Transcriptome and have some questions about the specifications for the striatum brain region. Within the interactive atlas, the striatum includes samples from the caudate nucleus, putamen, and nucleus accumbens. Is the transcriptome data from the striatum a combination of samples from all of these regions? How exactly are striatal samples taken from each donor?

Hello @teddyd, the Developmental Transcriptome work was performed by our collaborators and a portion of the work was described in this paper Spatio-temporal transcriptome of the human brain | Nature. Specifically check out the Supplementary Information pdf on page 9 and 10 for a description of what was included in the Striatum samples.


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Thank you very much!