New Imputed Gene Data for the Whole Mouse Brain Now Explorable in ABC Atlas

The ABC Atlas has been updated with new data!

This update adds the MERFISH imputed gene data created in Yao et al., adding more than 8,000 genes to the MERFISH dataset.

From the 10x scRNAseq whole brain data, additional gene expression was computationally imputed the into the spatial transcriptomic space (MERFISH) making 8,460 genes now searchable and explorable in ABC Atlas. This was done by searching for the k-nearest neighbors among 10xv3 scRNA-seq data for each MERFISH cell, using the 500 MERFISH genes.

Check out our GitHub resources to learn more. You can find downloads and more details describing the data here and a tutorial notebook showing examples on interacting with the data here.

As always, thank you for being part of the AIBS community. Please let us know how we can improve the ABC Atlas to better serve your needs.

1 Like