I have read the article “Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells,” and I greatly admire this work. I am currently conducting some related research, and I would like to ask a few questions about the methods they used to extract morphological features, as mentioned in the article. The article states that “The code for electrophysiological and morphological feature analysis and clustering is available as part of the open-source Allen SDK repository, IPFX repository, and DRCME.” The article “Classification of electrophysiological and morphological neuron types in the mouse visual cortex” also provides a similar response. I have the following questions:
- If I want to extract morphological features, which specific package and submodule should I use to calculate them, and can morphological features be extracted directly from raw SWC data files?
- If I use raw SWC data from other articles, can I extract morphological features using the same methods?
- Do you know if there is a database available that contains both transcriptomic and morphological data for the same cells?
I deeply appreciate your help. Thank you very much.