The Allen Institute for Brain Science is excited to share its latest release to the Genetic Tools Atlas (GTA). It adds a more than 750 datasets. These include 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
They further increase the GTA’s total coverage to:
- 3900+ experiments (including mouse & macaque)
- 2600+ Epifluorescence images
- 1100+ STPT images
- 80+ Light sheet images
- Thousands of adeno-associated viruses (AAVs) - 1100+ for cortical cell types, 800+ for basal ganglia cell types, and 280+ for thalamic cell types
- 110+ transgenic mouse lines
Genetic Tools Atlas is part of the growing Brain Knowledge Platform and opens up endless possibilities for groundbreaking discoveries and breakthroughs in neuroscience. It enables neuroscientists to identify genetic tools to precisely target brain areas & identify the distribution of relevant cell types for their research. They are available to the research community via distribution partners:
- Find AAVs on addgene.org
- See transgenic lines at The Jackson Laboratory.
We’re planning to release additional experiments and image data in regular intervals. We value your feedback. Please let us know what you think and what you’d like to see in future updates!
Go to Genetic Tools Atlas
Learn more on portal.brain-map.org
Feature improvements
Neuroglancer links utilize Neuroglancer config JSONs
Image viewing links in Neuroglancer were previously generated on the fly. They are now generated through Neuroglancer config JSON files instead. This allows scientists to more easily share image links as the unresolved links are significantly shorter.
The filepaths to these Neuroglancer config JSON files are available alongside with the zarr filesets via the file manifest download and can be accessed via in the allen-genetic-tools AWS Open Data bucket.
SmartSPIM light sheet microscopy images now in GTA
SmartSPIM light sheet microscopy images are now available in Genetic Tools Atlas. They are presented as maximum intensity projection images and are still viewable via the image preview and in neuroglancer. Learn more about light sheet images here.
Go straight to addgene from GTA
Entries in the Addgene ID column are now links. Scientists can now more easily go from GTA to addgene to order a given relevant enhancer for experiments in their own lab.
