Hello!
I have been working with the transcriptomic data in the ABC atlas and noticed something interesting: When using the log-transformed data and plotting the copy number of one transcript against another in a handful of cells, strict linear relationships seem to appear in the midst of the larger data, even when the broader correlation is a negative one. What explains these small trends?
This is very odd indeed! Which dataset is this in specifically?
The data is the Chromium 10x v2 log-transformed counts, filtering cells by subclass “MB Dopa” and plotting the counts of each transcript per cell. Notably this pattern shows up in most plots regardless of what gene is on the y-axis.